Biology of vascular endothelial growth factors.
Identifieur interne : 007A32 ( Main/Exploration ); précédent : 007A31; suivant : 007A33Biology of vascular endothelial growth factors.
Auteurs : Himadri Roy [Finlande] ; Shalini Bhardwaj ; Seppo Yl HerttualaSource :
- FEBS letters [ 0014-5793 ] ; 2006.
Descripteurs français
- KwdFr :
- Cicatrisation de plaie (physiologie), Facteur de croissance endothéliale vasculaire de type A (), Facteur de croissance endothéliale vasculaire de type A (physiologie), Humains, Lymphoedème (physiopathologie), Néovascularisation pathologique, Polyarthrite rhumatoïde (physiopathologie), Tumeurs (), Vaisseaux lymphatiques (cytologie).
- MESH :
- cytologie : Vaisseaux lymphatiques.
- physiologie : Cicatrisation de plaie, Facteur de croissance endothéliale vasculaire de type A.
- physiopathologie : Lymphoedème, Polyarthrite rhumatoïde.
- Facteur de croissance endothéliale vasculaire de type A, Humains, Néovascularisation pathologique, Tumeurs.
English descriptors
- KwdEn :
- Arthritis, Rheumatoid (physiopathology), Humans, Lymphatic Vessels (cytology), Lymphedema (physiopathology), Neoplasms (blood supply), Neovascularization, Pathologic, Vascular Endothelial Growth Factor A (classification), Vascular Endothelial Growth Factor A (physiology), Wound Healing (physiology).
- MESH :
- chemical , classification : Vascular Endothelial Growth Factor A.
- blood supply : Neoplasms.
- cytology : Lymphatic Vessels.
- chemical , physiology : Vascular Endothelial Growth Factor A, Wound Healing.
- physiopathology : Arthritis, Rheumatoid, Lymphedema.
- Humans, Neovascularization, Pathologic.
Abstract
Angiogenesis is the process by which new blood vessels are formed from existing vessels. The vascular endothelial growth factors (VEGFs) are considered as key molecules in the process of angiogenesis. The VEGF family currently includes VEGF-A, -B, -C, -D, -E, -F and placenta growth factor (PlGF), that bind in a distinct pattern to three structurally related receptor tyrosine kinases, denoted VEGF receptor-1, -2, and -3. VEGF-C and VEGF-D also play a crucial role in the process of lymphangiogenesis. Here, we review the biology of VEGFs and evaluate their role in pathological angiogenesis and lymphangiogenesis.
DOI: 10.1016/j.febslet.2006.03.087
PubMed: 16631753
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Angiogenesis is the process by which new blood vessels are formed from existing vessels. The vascular endothelial growth factors (VEGFs) are considered as key molecules in the process of angiogenesis. The VEGF family currently includes VEGF-A, -B, -C, -D, -E, -F and placenta growth factor (PlGF), that bind in a distinct pattern to three structurally related receptor tyrosine kinases, denoted VEGF receptor-1, -2, and -3. VEGF-C and VEGF-D also play a crucial role in the process of lymphangiogenesis. Here, we review the biology of VEGFs and evaluate their role in pathological angiogenesis and lymphangiogenesis.</div>
</front>
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